Technology Assessment Awardees

Universities:

Johns Hopkins University

Morgan State University

University of Maryland, Baltimore

University of Maryland, Baltimore County

University of Maryland, College Park

Johns Hopkins University

Developing a highly efficient, disruptive technology for biologics cell line development: ProtECT (Gould)
Affinity-cocktails of alpha-particle antibody-radio conjugates: treating early hepatic metastases of pancreatic ductal adenocarcinoma (Sofou)
Developing long-acting injectable IGF-1 to improve recovery after peripheral nerve injuries (Elhelali)
Developing a cell-targeted dendrimer-drug therapies for safe, convenient, and effective treatment of obesity and atherosclerosis (Kannan)
D-SENSE: deep learning-powered digital SERS for rapid and ultrasensitive bioprocess monitoring (Barman)
Developing a non-viral brain-penetrating gene therapy for effective treatment of Parkinson’s disease (Hanes)
A high-throughput cell line development platform to identify optimal clones for biomanufacturing of therapeutics (Kalhor)
Inhibiting nonsense-mediated decay generates neoantigens that stimulate a potent anti- cancer immune response (Kinzler)
Development of a through-the-scope clip for endoluminal defect suturing and dynamic tissue traction (Khashab)
Targeting PTP22 for cancer immunotherapy (Ho)
Development of a novel inhaled gene therapy, based on HAPLN1 transgene expression, for treating COPD (Sidhaye)
Targeting Antigen-specific CD4+ T cells for In[1]situ CAR-T Cell Generation for Immunotherapy (Schneck)
Advancement of a Blood based PD (Parkinsons Disease ) with Novel Analytics for Multi-Factor Readouts for disease staging (Mao)
Developing a First-in-Class Therapeutic Antibody for Treatment of Type-1 Diabetes (Hu)
Developing a Novel Single Particle Analyzer for High Resolution and High Content Characterization of Nanoparticle-Based RNA Therapeutics (Hsieh)
Developing a Neural Implant for Patients With Spinal Cord Injury (Manbachi)
Developing a High-Density Tactile Sensor Array with a Single Output Wire for Medical Rehabilitation (Thakor)
Development of an Immunotherapy for Prevention and Treatment of Type 1 Diabetes (Hamad)
Developing a Photoacoustic Imaging Device to Modernize Treatment of Peripheral Nerve Injury (Bell)
Development of Next-Generation, Brain-Penetrant Anthracycline Chemotherapeutics (Koldobskiy)
Developing a Microfluidic Platform for Detection of Rare Biomarkers from Non-Invasive Biological Sample Matrix (O’Keefe)
Development of DNA Nanotubes Containing Doxorubicin that Cross the Blood Brain Barrier to Treat Glioblastoma (Kokkoli)
Developing a Novel Tool for Diagnosing Epilepsy from Scalp EEG: EPIScalp (Sarma)
Development of an mRNA Booster for the Treatment of Haploinsufficiency Disorders (Coller)
Development of an Oncolytic Peptide as a Therapeutic for Rectal Cancer (Popel)
Developing a Novel Non-Invasive, Biomarker Test to Detect and Distinguish Prostate Cancer from Benign Prostatic Prostatic Disease (Pavlovich)
Delivery of HIF-1 mRNA to Improve Wound Healing (Harmon)
AI-powered Surgical Mentor: Ophthalmic Procedures (Sikder)
Accelerating Signal Processing of Infant Worn Vital Sign Monitor (Sen)
Development of an Inhalable Nintedanib Nanosuspension Formulation for Treating Fibrotic Lung Disease (Sidhaye)
Developing Kinetic mRNA Particles to Program CAR Macrophages In Vivo for Cancer Therapy (Mao)
Developing Novel Gastrojejunostomy Feeding Tube for Rapid Bedside Exchanges (Weiss)
Development of a Novel immune Stimulating Antibody (ISAC) Conjugate Against CD47 (Suk)
Developing a Novel Spectral Approach For Remote Risk Stratification and Screening of Colorectal Cancer (Mathews)
Detection of Strep Throat on a Telehealth Visit Using AI and Smartphone Video: StrepAI (Canares)
Developing an Oral GCPII Inhibitor for Inflammatory Bowel Disease (Peters)
Developing DPTIP-P12: an Orally Available nSMase2 Inhibitor for the Treatment of HIV (Rais)
Developing Biodegradable Nanofiber Funnel Conduit for Targeted Muscle Reinnervation (Tuffaha)
Development of a Chemical Dissolution Formulation to Facilitate the Breakdown and Drainage of Pancreatic Necrosis (Akshintala)
Developing Novel Hypoxia Inducible Factor Inhibitor to Treat Pathological Angiogenesis in the Eye (Sodhi)
Developing Chromobacterium-Based Biopesticide for Mosquito Control (Dimopoulos)
Developing Splicing-based vectors that enhance the efficacy of gene therapy for retinitis pigmentosa (Ling)
Developing CODA: A novel Clinical Decision Support System for Identification of Macroscopic Cancerous Regions Within Serial Sections (Wu)
Developing Next Generation Stem Cell Therapy To Treat Glioblastoma (Green)
Developing Novel Anti-proteotoxicity Therapeutic Agents Targeting Protein Methylation: Applications for Neurodegenerative Diseases (Wang)
Genetic Reprogramming of Tumor Cells In Situ for Systemic Cancer Immunotherapy (Tzeng)
Management of Unresectable Large Solid Tumors in the Liver by Engineered alpha-particle Radiotherapy (Sofou)
Developed Accumarker, an innovative tumor cavity localizer. This tool accurately localizes the borders of tumor cavity and diminishing the risk of excessive radiation. (Haibi)
Developing a novel platform for rapid point-of-care diagnosis-antimicrobial resistance prediction of sexually transmitted diseases (Wang)
Developing cytoplasmic transfer cell (CTC) therapy for retinitis pigmentosa treatment (Singh)
Development of a Non-viral, Redosable Gene Therapy to Treat Wilsons Disease (Kumbhari)
Developing CorFix: A Software for Medical Diagnosis and Pre-operative Planning for Fontan Surgery (Liu)
Developing a Novel Mini-Microscope for High-throughput Neuroimaging Applications and Drug Development: Pixela (Pathak)
Development of TrkB-antagonist ANA12 as novel adjunct treatment for refractory seizures in neonates (McArthur)
Vaso-Lock: Replacing Sutures for Faster, Easier, and Safer Microvascular and Vascular Anastomosis (Kang)
Developing Microfluidic Assay for Differentiation of Highly Metastatic Breast Cancer Cells (Konstantopoulos)
Developing ePACStim: Biomarker Driven Adaptive Brain Stimulation System for Parkinsons Disease (Anderson)
Developing A Precision Medicine Approach for Ovarian Cancer - Spiro Cyclic Guanidine RPN13 Inhibitor (Anchoori)
Developing a ProTide of 6-Mercaptopurine for Acute Lymphoblastic Leukemia (Lemberg)
Utilizing a dendrimer conjugated nSMase2 inhibitor to treat Alzheimers disease (Rais)
Sustained release epinephrine gels for use in Gastrointestinal Endoscopy (Kamal)
Developing Off-the-Shelf, Biodegradable Small-Diameter Tissue Engineered Vascular Graft for Arterial Conduit (Gerecht)
Developing B-TACT - Bortezomib targeted chemo therapeutic for treatment of liver cancer (Selaru)
Development of Bryostatin-1 as a novel remyelinating drug for multiple sclerosis (Kim)
Developing DifCons: diffuse-light-collecting integrated concentrators for light-weight, low-cost, ubiquitous solar energy (Thon)
Developing a Novel Sustained Release Therapeutic for Migraine and Facial Aesthetics - NanoTox (Reddy)
Developing a Novel Non-invasive Genomic Biomarker for Human Egg Quality (Das)
Developing a Naturally Derived and Easily Synthesizable PET Tracer for Specific Diagnosis of Bacterial Infections (Jain)
Developing Itaconate Prodrug JHU-142 to treat Alopecia Areata (Slusher)
Developing a Novel UAS Drone a Medical Product Transport System (Amukele)
Developing an AAV strategy targeting TDP-43 splicing repression to treat Inclusion Body Myositis (Wong)
Developing a MRI-Compatible Functional Cranial Implant for Pump-Assisted Chronic and Direct Medicine Delivery to Treat Neurologic Pathology (Gordon)
Development of APPX42, a PSA-activated Recombinant Chimeric Molecular Grenade for Metastatic Prostate Cancer (Isaacs)
OcuGel: Disruptive Technology for Improved Drug Delivery to the Eye (Ensign)
Engineered bispecific antibodies for targeted inhibition of cancer metastasis (Wirtz)
Development of Photoacoustic Diagnosis and Monitoring of Perinatal Brain Hypoxic-Ischemic Encephalopathy and Stroke (Graham)
Developing ultra-thin, high strength, drug-eluting structures for prevention of ophthalmic infection (Parikh)
Developing EpiWatch: A mobile health application for epilepsy management (Crone)
Development of humanized KCNK9 monoclonal antibody for treating KCNK0-expressing malignancies (Laterra)
Developing epigenetic modulation and induction of synthetic lethality for cancer therapy (Yegnasubramanian)
Developing kubanda cryotherapy: low-cost cryotherapy device for the veterinary market (Durr)
Developing novel persister antigen assay for improved detection of untreated and persistent lyme disease (Zhang)
Developing VecTech: Next generation automated mosquito surveillance tools (Acharya)
Developing a molecular profiling formalin fixed patient tumor tissue: novel ligation in situ hybridization sequencing (LISH-seq) platform (Larman)
Developing a high efficiency sensor for diagnosis of real time electrolyte imbalance Cystic Fibrosis Monitoring (Searson)
Developing vapor sensing technologies based on stabilized organic transistors (Katz)
Developing SuperPACS: AI Enhanced Tools for Clinical Stratification of Patients at Risk for Cardiac Disease (Ambale Venkatesh)
Development of T417, a first-in-class inhibitor of the proto-oncognene PBX1 for the treatment of ovarian cancer and other human malignancies (Wang)
Developing a tool for early prediction of patients with sepsis who will develop septic shock: ShockAlert (Winslow)
Developing patient derived organoid models (PDO) predicting response to therapy in liver cancer (Selaru)
Developing a novel technology for determining the personalized optimal ablation targets in patients with atrial fibrillation (AF) and fibrosis (Trayanova)
Developing a potent rBCG as a therapeutic intervention for nonmuscle invasive bladder cancer (Bishai)
Developing an inhibitor of neutral sphinghomyelinase2 for the treatment of Alzheimer’s disease (Rojas)
Developing a novel therapy initially for triple negative breast cancer (TNBC) with potential for use against many other cancers (Semenza)
Optimization of an improved formulation of Mebendazole for treatment of brain and other cancers (Riggins)
Developing software for rehabilitation healthcare analytics & prediction (ReHAP) (Gourab)
Developing a multicomponent inhibition of hypoxia inducible factor to treat ocular neovascularization (Green)
Developing a minimally invasive theranostic device for brain neurooncology (Manbachi)
Developing a novel biomarker and ELISA assay for determination of cognitive status in Alzheimer’s disease (Worley)
Developing a therapeutic to prevent kidney toxicity in prostate cancer patients receiving PSMA-targeted radiotherapy (Slusher)
Developing a device to more accurately target spine during lumbar punctures (LP) to collect cerebrospinal fluid(CSF) (Moghekar)
Developing a method to use non-contrast-enhanced MRI and Perfusion index Mapping (Qin)
Developing a drug, Ethoxyquin-6, for prevention of chemotherapy-induced peripheral neuropathy (Hoke)
Develop a polyionic papillomavirus-like particles (VLP) for the treatment of prostate cancer (Viscidi)
Development of Hypoxia Inducible Factor-1 with Polymeric Chitosan Nanoparticles to improve wound healing (Harmon)
Developing the Corrie Health Digital Platform: Reinventing cardiac recovery (Martin)
Developing Intra-ART: A novel platform for MRI-guided intra-arterial placement of therapeutic agents to treat brain tumors (Pearl)
Developing a novel device for effective minimally invasive treatment for urethral strictures (Wright)
Developing a cohesive robot-ultrasound probe for prostate biopsy (Stoianovici)
Development of immunoswitch for treatment of metastatic melanoma: a novel immunomodulator approach (Schneck)
Developing a halofuginone as a disease-modifying therapy for osteoarthritis (Cao)
Developing a VLM-modified s-Ontak: a second-generation, Treg-depleting immunotherapy (Bishai)
Developing a cardiac RF ablation lesion assessment system (Karmarkar)
Developing a first non-invasive ELISA assay for pulmonary arterial hypertension (Everett)
SMART surgical tools: optical coherence sensor guided microsurgical tools with enhanced surgical fun (Kang)
“Smart” programmable digital stethoscope (Elhilali)
Developing a novel blood/sputum diagnostic test for lung cancer (Brock)
Developing a novel thyroid cancer specific biomarker panel (Umbricht)
Developing a precision medicine approach for treating a subtype of severe pain called allodynia (mechanical pain)(Bosmans)
Developing a new class of therapeutic compounds for the treatment of diarrhea predominant irritable bowel syndrome (IBS-D) (Barrow)
Developing an injectable nanofiber-hydrogel composite for soft tissue reconstruction (Sacks)
Developing a long-acting therapy for Parkinson’s Disease (Ko)
Developing an Epigenetic based test for the prediction of postpartum depression in pregnant women (Kaminsky)
Developing a 5-HT1A-Receptor: Biomarker stratification of patients with suicidal risk during treatment of pediatric depression (Kaplin)
Developing the Renalert System, a monitor for real time renal perfusion which enables clinicians to prevent acute kidney injury (AKI) (Hogue)
Repurposing of Cethromycin (QB101) for Malaria Prophylaxis (Sullivan)
Developing a new, first-in-class therapeutic to treat a heritable form of retinal degeneration called Leber’s congenital amaurosis (LCA) (Bunz)
Developing a new treatment for the autoimmune rheumatic disease, systemic sclerosis(SSc) (Lee)
Developing a small molecule PSMA inhibitor to treat Inflammatory Bowel Disease (Hartman-Ph.2)
Developing an imaging (FBnTP) agent as a biomarker for tumor aggressiveness and response to chemotherapy in early detection (Madar)
Develop color-coded quantitative brain cancer mapping for real-time, cost-effective surgical guidance. (Li)
Develop a therapeutic vaccine as a novel treatment for neuromyelitis optica (NMO) (Levy)
Develop a potent drug with a novel mechanism for the treatment of leukemia and lymphoma (Slusher)
Develop a novel tool for seizure localization in medically refractory epilepsy (Sarma)
Developing bifunctional immunostimulatory antibodies for treatment of cancer (Bedi)
Develop REMS: Robotic ENT Microsurgery System (Taylor)
Develop codeDNA: Advanced Malware Variant Detection (Breiner)
Developing biodegradable aAPC particles for cancer immunotherapy (Green)
Developing a drug to reverse atherosclerotic heart disease in diabetic mice (Chatterjee)
Develop an adaptive robotic platform for expandable, easy to program collaborative industrial robots (Hager)
Developing a saliva based rapid diagnostic test for detection of asymptomatic carriers of the malaria parasite (Dinglasan)
Improve delivery, enhance efficacy, and prolong glutaminase inhibitor drug levels in the tumor with the ultimate goal of improving outcomes for pancreatic cancer patients (Le)
Developing LiFi enabled 3D Optical Imaging for collision safety and autonomous transportation (Torruellas)
Improving computer-assisted craniomaxillofacial surgery (Gordon)
Using cell permeable peptides derived from Pirt2 mutant protein to treat chronic pain (Dong)
Developing a device that will reduce reoperation rates in breast conserving surgery. (Benkoski)
Developing a blood test based on methylated gene markers for breast cancer. (Sukumar)
Developing an inexpensive tool, called FastStitch, to improve the surgical suture process. (Nguyen)
Creating a device to assess cardiac filling pressure for preventing re-hospitalization for heart failure. (Silber)
Introduced a diagnostic method for rapid detection of significant coronary heart disease. (McVeigh)
Developing a cancer targeting agent, which has special relevance in castration-resistance prostate cancer (In collaboration with University of Maryland, Baltimore County). (Laiho)
Developing a device, called MouthLab, to enable the fast sampling of medical data. (Fridman)
Developing a new lotion to augments wound healing, improves healing skin quality and reduces scar size. (Walston)
Developing a polymeric fore sensor that is used with middle ear titanium prostheses to provide feedback to the surgeon. (Francis)
Developing non-invasive quantitative CT imaging-based alternative that will provide accurate and rapid determination of the functional significance of coronary artery disease. (Lardo)
Evaluating the efficacy and toxicity of artemisinin dimers in a mouse model and to select the lead dimer for further development towards clinical studies in humans. (Boger)
Develop a prototypic nanoparticle based system to mediate redirected lysis by human antigen-specific cytotoxic T lymphocytes, CTL, to tumor cells that would otherwise not be recognized. (Schneck)
Developing a technology to use autologous volar fibroblasts to create new thick skin at the stump site for amputees. (Kang)
Commercialize novel chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) biosensors. (van Zijl)
Developing a peptide-based therapy for acute and chronic diahrreal diseases. (Zachos)
Developing a more effective treatment for seizures using amino acid therapy. (Hartman)
Developing a low cost, high speed, wide dynamic range, software configurable, multimodel imaging sensor. (Rizk)
Developing Standardized Manufacturing and Sterilization of Customized Bio-Bone Scaffolds for Treating Midfacial Bone Defects. (Grayson)

Morgan State University

Developing a Portable Quantum Sensing Device (Ozturk)
Designing a Shoe for Individuals with Diabetes: The Davis Walker™ (Jamaludeen)
Developing a Universal Novel Nanoscale Electrode for High Resolution Applications (Ozturk)
Developing SUMZ: A stormwater utility management system (Hunter)
Developing LightTrax: a building occupant lighting tracking system (Nyarko)
Developing technology that offers a cost-effective and environmental friendly alternate to produce biofuel using naturally available sea water and the sun’s energy. (Early Charm Ventures-Ph.2)
Developing the iCrystal System and new crystallization platforms for rapid drug treatment. (Aslan-Ph.2)
Development of a bilateral corneal symmetry 3-D analyzer (Mehravaran)

University of Maryland, Baltimore

Optimization of wNMR for Real-World Applications (Yu)
LNP-Echinomycin, a nanoparticle-encapsulated anti-cancer agent formulated with novel oligonucleotide-hitchhiking technology (Wang)
Developing Cell-HKer/siRaf, a promising therapeutic for Solid Tumors (Ames)
Development of a novel optic nerve-stem cell therapy for glaucoma prevention and treatment (Bernstein)
Development and Evaluation of a C. difficile-Specific Endolysin and Dual Therapy for C. difficile Infection (Li)
Developing a Fiberoptic Arterial Catheter to Measure Real-Time Intravascular Oxygen Saturation and Blood Pressure (Buehler)
Developing a Novel Medical Device to Non-invasively and Conveniently Monitor Intraocular Pressure (Isaiah)
Development of a Novel Percutaneous Access Graft for Improved Patient Care (Griffith)
Development of a Synthetic Bovine Colostrum as a Unique Anti-Inflammatory and Growth-Enhancing Food Additive for Poultry Farming (Cross)
Developing HTLA: A Scalable Platform to Produce Completely Synthetic Gene Therapy Vectors (Li)
Developing Early identification of shock with a novel point-of-care test for serum renin (McCurdy)
Third Lung: A Device for Providing Oxygen and Removing Carbon Dioxide without Using the Lungs (Friedberg)
Development of a small molecule GPR68 inhibitor, a novel therapeutic class for the treatment of acute respiratory distress syndrome (Hong)
Novel Axin Stabilizer YA6060 is a Promising Therapy for Nonalcoholic Steatohepatitis (NASH) (Shu)
Developing Antipseudomonal Agent GalSal: A Dual Inhibitor of Pseudomonas aeruginosa Heme Sensing and Iron Uptake (Xue)
Delivery of the CIB2 Gene to the Retina as a Therapy for Dry AMD (Ahmed)
Developing the POD-Vis cloud-based platform generates actionable insights from complex clinical datasets (Shulman)
Developing NEU1-Selective Sialidase Inhibitors for Treatment of Idiopathic Pulmonary Fibrosis (Goldblum)
Development of the DART Therapeutic Nanoparticle Platform for Fn14-Positive Cancers (Kim)
Developing a Handheld Point-of-Care Device to Detect Impending Catheter-Associated Urinary Tract Infection (CAUTI) (Srinivasan)
Developing a Blood Diagnostic for Assessing Head and Neck Cancer Histological Immune Profile (Younis)
Developing YW2065 with dual activities of Wnt/Beta-Catenin inhibition and AMPK activation for colorectal cancer (Xue)
Developing novel anti-malarial ART631 as a potential leukemia treatment (Civin)
Reinventing transplant transportation: teal-time organ management using the HOMAL and COM App (Scalea)
Developing a novel high-efficacy approach to cancer immunotherapy with minimal toxicity (Davila)
Developing Elabela into a therapeutic for heart failure (Gong)
Developing a transseptal puncture device for left atrial access (Gammie)
Developing a diagnostic for non-small cell lung cancer (Jiang)
Developing next-generation multi-specific antibody therapeutic (Li)
Developing a novel bifunctional antibody for lung cancer therapy (Ren)
Developing a novel transRectal Focal Abdominal Cooling (rFAC) device for the treatment of IRI and SIRS (Hu)
Developing a blood test for the early detection of lung cancers based on newly-discovered sprRNAs (Mei)
Using Synthetic Inhibitory Mucin Protecting Lung Epithelia (SIMPLE) technology to treat pseudomonas lung infections (Lillehoj)
Developing a first-in-class therapy for sepsis (Vasta)
Developing a portable deficit-adjusted ankle robot for neurologically disabled populations (Macko)
Optimization and Validation of a Novel Immunotherapy against Clostridum difficile Infection (CDI). (Feng)
Developing a novel system for recombinant protein expression. (In collaboration with University of Maryland, College Park) (Robb)
Refining and validating the first universal cancer immunotherapy, At-CAR (Anti-tag Chimeric Antigen Receptor). (Davila-Ph.2)
Developing a new target and approach to antibiotic therapy (Wilks)
Using magnetic nanoparticles for the treatment of dental disease (Masri)
Developing VNLG-152 as a novel targeted therapy for triple negative breast cancer (Njar)
Developing a technology for Alzheimer’s disease therapy that targets an inflammatory pathway in asymptomatic and symptomatic patients. (Zimmer)
Develop a method to rapidly assess the function of NKT cells in cancer patients (Webb)
Developing anti-thrombosis antibody product to improve clinic treatments (Xu)
Developing a novel hybrid mesh for the treatment of pelvic organ prolapse. (ZSX Medical-Ph.2)
Developing a technology, called RelaxDetect, which can detect biopharmaceutical aggregation via water relaxation in sealed vials. (Bruce Yu)
Develop a thermal endoscope for laparoscopy. This technique will reduce serious intraoperative complications by over 50%. (Pearl)
Commercialization of an Inflammatory Bowel Disease (IBD) diagnostic based on a microbiome signature technology. (ITVMD-Ph.2)
Developing an interactive web-based software that will be commercialized for detecting and addressing parental psychosocial risk factors for child abuse/neglect within healthcare settings. (Dubowitz)
Develop a unique opioid analgesic with reduced tolerance. (Coop)
Developing a topical cream for treatment of cervical intraepithelial neoplasia. (Khanna)
Developing a device for Noninvasive Detection of Injury-Site Oxygen Deficiency and Excessive Pressure of Compartment Syndrome. (Zhang)
Developing MyoNOsen; A Novel Oligonucleotide Therapy for Hypertension and its Sequela, Heart Failure (HFpEF). (Fisher)
Measurement of Reactive Oxygen Species to Assess Red Blood Cell Quality. (Kao)
Developing the AVAD-2, an Automated Vascular Access Device for Lifesaving Procedures. (Sarkar)
Developing a Novel, Safe and Protective Zika Vaccine. (Li)

University of Maryland, Baltimore County

Developing AI-enabled multi-sensor vest for real-time situational awareness in high-risk operations (Gangopadhyay)
REVLR™: An Immersive Modeling and Data Visualization Environment (Boot)
Development of NitraSense™: A Portable Water Quality Analyzer (Kumar)
Developing “BreathShake”: Next-Generation Breathable Shake Flask (Srinivasan)
Developing "ScanMaster" - Mirror-Assisted Continuously Scanning Laser Vibrometry for Measuring Three-Dimensional Panoramic Vibrations of Structures (Zhu)
Harvesting Lithium & Uranium from Landfill Coal Slurries and Brines (Al-Sheikhly)
FlexiCharge: Flexible Thermoelectric Generator for Wearable Health Monitoring Devices (Madan)
Developing Heteroduplex Thermostable Ligase Assembly (HTLA): A Rapid and Cost-Efficient Technology to Construct Large DNAs (Bieberich)
Developing GlucoSense: Binding Protein-Based Biochemistry Analyzer (Rao)
Developing "TrackingStar" - A Zero-Contact Tracking System for Wind Turbine Health Monitoring (Zhu)
Developing Energymaster - a Floating Hybrid Tidal/Wave/Wind Energy Harvesting System (Yu)
Developing GraphCAN: Graph-Based Algorithms for Secure Vehicular Communication (Islam)
Developing a Data Quality Toolkit (Koru)
Creating safe and flexible alkaline rechargeable Zn batteries (RZB) (Madan)
Developing Flex-nucleosides to treat SARS-CoV-2 and COVID-19 (Seley-Radtke)
Develop 'Transfinity' an Infinitely-variable Transmission for Tidal Energy Harvesting (Zhu)
Developing a System for Privacy Management Using Condensation-Based Differential Privacy: MITIGATE (Chen)
Developing a new high-efficiency DNA cloning platform for synthetic biology applications: ExSembly (Li)
"Windmaster" - an Improved Hybrid Vertical Axis Wind Turbine (Yu)
Developing a System for Vulnerability IdeNtifiCatIon (VINCI) (Karabatis)
Developing a NanoQuineTM: Nanoparticle-Encapsulated Antimalarials to Treat Lupus Nephritis (Szeto)
Building a scalable and intrusion-tolerant permissioned blockchain system (Zhang)
Developing an innovative three-drug therapy for acute myeloid leukemia (Bieberich)
Apogee scanner, a laser-based spectrographic system for stand-off detection of trace materials (Arnold)
Development of bidirectional cannula for arterial access for extracorporeal life support (Griffith)
FlexVib - Robotic continuously scanning laser doppler vibrometry (Zhu)
Developing DL5016 as an enhancer for cyclophosphamide-based chemotherapeutics (Wang)
Development of NCGC-43 as a novel fast-acting antidepressant (Thompson)
Developing a way to detect antibiotic-resistant bacteria in blood (Kostov)
Developing a novel drag reduction approach for box trailers TrimJET (Farquhar)
Developing an impact-driven piezoelectric energy harvester: ActiveCharge (Lee)
LifePower: a self charging power source for implantable devices (Slaughter)
SolarSafe: a long-lead-time forecaster of solar storms (Savani)
Developing ‘substrate-cage: devices for novel enzyme discovery (Gardner)
Developing small molecule pyrimidines potent anticancer therapeutics (Seley-Radtke)
Developing a commercialization plan for CRAFT cybersecurity system (ITVMD-Ph.2)
Develop an immunotherapy drug (BiTE) for the treatment of cancer. (Ostrand-Rosenberg)
Developing an App for real-time audience enhancement and music education during music presentation and concerts. (Dusman-Ph.2)
Biomarker discovery and validation for Kinase Inhibitors (Bieberich)
Developing a geared infinitely variable transmission with minimal speed fluctuation. (Zhu)
Working to increase food safety and agricultural productivity through innovative feed additives. (MycoInnovation)
Developing soluble CD80 (CD80-Fc) as a therapeutic agent for the treatment of cancer. (Ostrand-Rosenberg)
Develop and evaluate the efficacy of a recombinant NNV (Nervous necrosis virus) vaccine. (Vakharia)
Produce a bioamended activated carbon pellet seeded with PCB- degrading microorganisms to reduce the concentration of polychlorinated biphenyls (PCBs) in sediments. (Sowers)
Developing a sensing system comprising of ultra-low cost textile-based nonrigid capacitive sensor arrays and inertial sensors that allow individuals with upper extremity paralysis to control their appliances and security systems remotely. (Banerjee)
Developing multi-site TMS Tools for improving Impaired Brain Connectivity. (Choa)
Development of HoloMentor: eXtended Reality (XR) for Clinical Telementoring. (Mentis)

University of Maryland, College Park

AI-Augmented Quantum Diagnostics of Ovarian Cancer: A scalable production of OCC-DNA sensor arrays (Wang)
Emergente – Integrating AI and physics to model RNA structures with therapeutic potential (Tiwary)
Developing a universal rapid, ultrasensitive, and selective biological diagnostic and detection system based on epitaxial graphene (Daniels)
Automating language assessment: Enhancing DLD diagnosis for bilingual children (Ortiz)
Innovation in Nipple-Areola Complex Reconstruction (Fisher)
Development of genetically programmed high-yield biomanufacturing of probiotic bacterial extracellular vesicles (Jay)
Utilizing Natural Language Processing Technology for Creating Inclusive Classrooms (Killen)
Developing the Baby Gro Pro Smartscale: improving early diagnosis of medical problems and rare disease (Aroom)
Developing a Bioimpedance Capsule System for Monitoring Epithelial Tissues in the GI Tract (Ghodssi)
Developing a Light-Activatable, Sustained-exposure Ethanol Injection Technology (LASEIT) for Locally Advanced, Unresectable Tumors (Huang)
Developing Eco-Friendly Soft Materials That Can Absorb Impact and Protect Fragile Objects (Raghavan)
Development of Tunable Energy Absorbing Materials to Enhance Safety and Crashworthiness (Wereley)
Development of an Ultra-High Coupling Efficiency Fiber-to-Chip Coupler for Photonic Integrated Circuit (Zhang)
Developing a Carbon-Sequestration Building Insulation Materials: Recycling Agriculture Waste for Sustainable Thermal Insulation Panels (Ren)
Creating Quantum Modems and Routers to Build Quantum Networks (Waks)
Developing a Compact Chip for Laser Injection Locking and Optical Parametric Oscillation (Lu)
Development of a Dual-Cup Reverse Shoulder Implant (Wang)
Developing Reliable AI (RELAI): a Platform to Efficiently Design, Train, Inspect and Improve AI Systems (Feizi)
Employing Smart Underwear in a novel inclusive diagnostic test for SIBO (Hall)
Developing a Reversible Electro-Adhesion of Hydrogels to Tissues: Enabling Suture-Less Surgeries (Raghavan)
Creating “Dost”: A Smart Virtual Friend That Can Talk, Interact, and Feel, Just Like You! (Bera)
Developing IRIS Reads: A literacy intervention/instruction App that is implemented as a suite of "mini-games" that crosses augmented (AR) and virtual reality (VR) platforms (Bolger)
Developing Highly Secure Anticounterfeiting Tags with Deep Learning Software for Reliable (Chen)
Retraining the immune system with lymph node depots to induce durable remission in type-1 diabetes (Jewell)
Developing an autonomous delivery robot with learning-based dense crowd navigation capabilities (Manocha)
Developing Artificial Intelligence software for assessment of posture and form in violin instruction (Fermuller)
Developing Sensitive Hybrid Nanosensors for Meat Freshness Monitoring (Gong)
Developing capacitive touch cuffs to track hand and finger gestures (Vaughn-Cooke)
Developing plant gene editing with novel CRISPR-Cas12 systems (Qi)
Electroformation: A Low-Cost Alternative for 3D-Printing of Biocompatible Hydrogels (Raghavan)
Managing Integrated Cyber Risk (Harry)
Manufacturing VacuGlass: Low-cost Vacuum Insulated Windows (Kim)
Developing a Resonate Pulsating Combustion System for Flow Control Applications (Flatau)
Developing a Scalable High Power Narrow Linewidth Semiconductor Laser for Self-Driving Car Using FMCW LiDAR (Dagenais)
Developing a Bacteriolytic Enzymes against Proprionibacterium acnes for Treatment of Acne Vulgaris (Nelson)
Developing Autothermal Catalytic Wall Reactor for Natural Gas to Liquids (Liu)
Developing a Shock Synthesis of Nanoparticle Alloys for Ammonia Oxidation (Hu)
Development of an on-chip microelectrode solution chemistry sensor for liquid cell electron microscopy (Woehl)
Developing an Integrated Onboard Charger and Smart Control System for Electric Vehicles (Khaligh)
Developing CATA: Cyber Aptitude and Talent Assessment (Bunting)
Developing flexible bioelectric sensor for detection and inhibition of biofilm (Ghodssi)
Staggered electrode multi-battery for emerging on-board power applications (Rubloff)
Developing MCube: A building energy monitoring, modeling and management software system (Srebric)
Creating real-time 3D prinitng, quality assurance and product acceptance testing (Schultheis)
Developing an add-on Brillouin biomechanics module for confocal microscopes (Scarcelli)
Developing VOLT: a tailored occupation specific language training in immersive virtual reality environments (Bunting)
Developing a mucosal vaccination against RSV infection (Li)
Developing a recurrent processing unit (RPU) for high performance computing (Lathrop)
Building-scale weather and energy forecast service (BuildECast) for electricity savings (Jin)
Developing novel polyphosphazene technology for stabilizing protein therapeutics (Andrianov)
Developing targeted enzymes for effective treatment of lysosomal disorders (Muro)
Developing drought-tolerant crop cultivars with improved water-use efficiency (Xiao)
Develop QUANTITY: A novel analysis kit for protein drug development (In collaboration with Johns Hopkins University). (Li)
Developing an integrated power electronic charger/converter for plug-in electric vehicles. (Khaligh)
Developing an efficient mucosal vaccination mediated by the Neonatal Fc Receptor. (Zhu)
Creating hemostatic bandages based on a new biocompatible polymer (In collaboration with University of Maryland Baltimore). (Raghavan)
Developing and testing protocols for scour sensing post deployment. (Tauros-Ph.2)
Developing novel acyclic cucurbituril molecular containers as broad spectrum reversal agents for neuromuscular block agents used during surgery. (Isaacs)
Developing a clinical assay that would provide a tool to improve time to diagnose and monitor disease progression in ALS and possibly other neuromuscular diseases (In collaboration with University of Maryland, Baltimore). (Chin)
Developing a vaccine against a significant swine pathogen, procine reproductive and respiratory syndrome virus (PRRSV). (Zhang)
Developing 2D hyperspectral imaging techniques for manufacturing yield and device failure analysis for photovoltaic cells and LEDs. (Bartolo)
Develop a new technology for the production of liposomal nanoparticle drugs in a unique continuous-flow manufacturing process. (DeVoe)
Develop data analysis tools on a user-friendly web interface and customize them for a variety of clients ranging from national chain restaurants to other establishments and local health departments in searching the existing nationwide food safety inspections database. (Bederson)
Developing a novel, generalized approach to the formulation of vaccines against Gram-negative pathogens (In collaboration with University of Maryland, Baltimore). (DeShong)
Customize Behavioral Activation Treatment for Depression (BATD) for a mobile platform to be used by clinicians and their patients by creating a BATD mobile application to be used in conjunction with therapy. (Lejeuz)
Developing a non-invasive way to evaluate the quality of a donor kidney known as kidney viability assessment system (KVAS). (Chen)
Engineering an All-natural, Eco-friendly Foam for Highly Efficient Atmospheric Water Harvesting. (Li)
Machine Intelligence-Accelerated Discovery and Production of All-Natural Plastic Substitutes. (Chen)